Research grants

Introduced in 2001, Lefoulon-Delalande Foundation research grants are awarded annually to support the work of postdoctoral researchers working full time in cardiovascular science at a French research institute (research internships in other countries are not eligible).

The focus of research may be cardiovascular development, physiology, pathologies, epidemiology, medical therapeutics or surgical therapeutics, excluding research into cancers.

Candidates must hold a doctorate or equivalent qualification in medicine, science, pharmacy or veterinary medicine.

A jury of between six and eight French scientists selected the winning candidates: Professors Ziad Mallat (Chairman of the Jury), Gisèle Bonne, Damien Bonnet, Michel Desnos, Anne Eichmann, Rodolphe Fischmeister and Gervaise Loirand

Jury members

Ziat Mallat
Gisèle Bonne
Damien Bonnet
Michel Desnos
Anne Eichmann
Rodolphe Fischmeister
Gervaise Loirand

Past

recipients

2021

  • Rida Al Rifai
    Pathophysiology of experimental dissecting aortic aneurysm during JAK2V617F positive myeloproliferative syndromes
  • Florian Alonso
    Fibrillin-1: a new actor in angiogenesis, an exploration of its therapeutic potential for vascular repair
  • Louise Benarroch
    Identification of genetic modifying factors in laminopathies affecting striated muscles
  • Pierre Bobin
    Production of cardiac pseudo tissues derived from human induced pluripotent stem cells as a preclinical study model for Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)
  • Aurélien Bustin
    Automatic extraction of sudden death risk markers combining black blood MRI of myocardial scars and artificial intelligence
  • Guido Caluori
    Cardiac aging and induced remodeling in atrial fibrillation
  • Stéphane Camus
    Efferocytosis and control of myocardial remodeling by macrophages
  • Victor Charpentier
    Customized expandable balloon stent for pediatric and congenital heart disease
  • Damien Huzard
    The importance of affective touch in the mechanisms of cardiac regulation by the vagus nerve: the role of ‘C-tactile’ sensory fibers in heart rate variability and regulation of social behaviors in models of autism.
  • Kanchan Kulkarni
    A new method of pacing to prevent the development of ventricular tachyarrhythmias during chronic myocardial infarction
  • Mathieu Panel 
    Spatio-temporal study of neuroinflammatory remodeling during heart failure in mice
  • Barbara Ribeiro
    High-throughput phenotyping of KCNH2 gene variants encoding the hERG cardiac potassium channel
  • Natalia Smirnova
    Influence of humoral immunity on the vessel wall in transplant vasculopathy
  • Almudena Val Blasco
    Sodium- and calcium-dependent proarrhythmic mechanisms in catecholaminergic ventricular tachycardias

2020

  • Isabel Alves : The importance of modifying genetic factors and pleiotropy in (cardiac) rhythm disorders: an integrative approach to Brugada Syndrome
  • Caroline Choquet : Decoding the ‘cardiac code’: identifying the molecular and cellular mechanisms directing the temporal and spatial specification of early cardiac progenitors in mice
  • Pierre-Michaël Coly : The effects of hemodynamic forces in the formation and incorporation of extracellular vesicles by endothelial cells, and their potential role in atherosclerosis
  • Emilye Hiriart : Complement cascade involvement in the cerebrovascular lesions of COL4A1/A2-related disorders
  • Rima Kamel : Phosphodiesterase gene therapy for heart failure
  • Ahmed Karoui : Study of the cardioprotective role played by NMRK2 kinase in NAD coenzyme synthesis as a response to myocardial ischemia/reperfusion stress
  • Caroline Le Dour : The role of lipotoxicity in dilated cardiomyopathy resulting from LMNA gene mutations
  • Nassim Mahtal : Study of the role played by Vasorin in the maintenance of pericytes and microcirculation
  • Nawal Maissa : ‘On demand’ opening of the blood-brain barrier
  • Marine Martinez : The role played by the conduction system on repolarization heterogeneity and ventricular fibrillation in a large mammal model of chronic infarction
  • Anja Nitzsche : Modulation of the vascular protective signaling effect of sphingosine 1-phosphate
  • Chloé Rafael : Involvement of the renal NaCl secretion pathway in the pathophysiology of hypertension
  • Jairo Rodriguez-Padilla : Classification of electrical signals to guide arrhythmia ablation
  • Nadine Suffee : Characterization of the atheroprotective mechanism of innate lymphoid cell type 2 (ILC-2)

2019

  • Renée Chow : Study of the role played by mechanical forces induced by cardiac contraction during heart valve formation in zebrafish
  • Guillaume Coutance : Optimizing the cost-effectiveness of endomyocardial biopsy in cardiac transplant recipients through the creation and validation of an individualized risk stratification tool for cardiac allograft rejection
  • Audrey Desgrange : Deciphering the mechanisms behind asymmetric morphogenesis of the heart
  • Thomas Hof : Study of TRPM7 (Transient Receptor Potential Melastatin 7) channel involvement in conditions related to cardiac electrical activity
  • Claire Leclech : The influence of biophysical signals on the organization and functionality of a vascular endothelial cell monolayer
  • Marta Lindner : The effects of FGF23 and αKlotho on the prevention of cardiovascular morbidity and mortality
  • Stéphanie Paradis : The role of photobiomodulation in advance warning of intermittent hypoxia-induced myocardial injury via inhibition of Hypoxia-Inducible Factor-1
  • Laetitia Pereira : O-GlcNAcylation of Epac as a novel regulator of cardiac Ca2+ signaling
  • Antoine Rimbert : Identification of new regulatory mechanisms governing plasma LDL-Cholesterol levels

Research grant renewals :

  • Emilie Dubois-Deruy : Regulatory mechanisms associated with superoxide dismutase 2 in heart failure: the involvement of acetylation
  • Icia Santos-Zas : Exploration and modulation of CD8+ T cells in postinfarction cardiac remodeling

2018

  • Sophie Burel : Phosphorylation and FGF13: Roles in Cardiac NaV1.5 Channel Regulation
  • Emilie Dubois-Deruy : Regulatory mechanisms associated with superoxide dismutase 2 in CI: the involvement of acetylation
  • Anne-Laure Duchemin : The role played by hemodynamic forces during ventriculobulbar valve morphogenesis in zebrafish
  • Emilie Faure : Study of the role played by krox20 factor in aortic valve endothelial cells and study of the role played by hemodynamics in valve degeneration
  • Bamba Gaye : The therapeutic potential of non-coding RNAs and their use as biomarkers in vascular pathologies such as abdominal aortic aneurysm (AAA)
  • Youmna Ghaleb : Identification of new genes in Familial Hypercholesterolemia using next-generation sequencing
  • Edyta Glogowska : The role played by Piezo1 in pulmonary hypertension
  • Nicole Karam : The influence of gender on survival following ischemic cardiac arrest
  • Peter Langfield : Assessment of arrhythmogenic risk as a result of repolarization heterogeneity in patient-specific models
  • Marianna Meo : Spatio-temporal analysis of the heart’s electrical signals for atrial fibrillation ablation
  • Alice Recalde : New therapeutic targets in atrial fibrillation: the role played by Epac
  • Baptiste Rode : New therapeutic targets in atrial fibrillation: the role played by Epac
  • Icia Santos-Zas : Exploration and modulation of CD8+ T cells in post-ischemic cardiac remodeling

Research grant renewals :

  • Laetitia Andrique : 3D modeling of artificial vessels: an appropriate tool for analysis of vasculogenesis
  • Silvia Bottini : Investigation of a novel genomic function of the Ro60/s-RNY ribonucleoprotein complex in foamy macrophages
  • Thomas Mathivet : A window on vascular pathologies: study of vascular dynamics using in vivo multiphoton imaging

2017

  • Laetitia Andrique : In vitro production of mature blood vessels using 3D vascular tissue engineering
  • Claire Angebault : Involvement of the sarcotic/endoplasmic reticulum – mitochondria interaction in Duchenne Muscular Dystrophye
  • Feriel Azibani : Late anthracycline-related cardiotoxicity in pregnancy and postpartum
  • Daria Bonazzi : Study of the role played by membrane tension in regulation of the cellular response during meningococcal infection
  • Silvia Bottini : Functional characterization of the Ro60/s-RNY ribonucleoprotein complex in foamy macrophages
  • Pedro Campinho : Endothelial cell dynamics and tissue mechanics during dorsal aorta development
  • Romain Capoulade : Pathophysiology of mitral valve prolapse: multi-modality imaging, animal model and genetics
  • Rachel Climie : The predictive value of baroreflex sensitivity for cardiovascular incident events in the general population
  • Fabienne Lescroart : Defining the cellular and molecular heterogeneity of cardiac progenitors during murine embryogenesis
  • Thomas Mathivet : A window on pathological vasculature: the use of multiphoton technology for in vivo murine imaging. Stroke and hereditary vascular diseases HHT and ehlers danlos syndrome (vEDS)
  • Gleb Novikov : The molecular mechanisms of the AT1R response to mechanical stimuli, the role of sodium and identification of new therapeutic targets

Renouvellements de bourse :

  • Fabrice Antigny : Potassium channel KCNK3 involvement in the development of pulmonary hypertension. An assessment of the relevance of therapeutics in targeting the KCNK3 channel
  • Grégory Franck : The mechanisms involved in atherosclerotic plaque erosion processes. The role of netosis and the MRP8/14 complex in a new model of erosion in mice
  • Florence Tatin : The role of apelin at intercellular junctions and immune cell recruitment in the lymphatic endothelium

2016

  • Fabrice Antigny : Potassium channel KCNK3 involvement in the development of pulmonary hypertension. An assessment of the relevance of therapeutics in targeting the KCNK3 channel
  • Caroline Cros : The role of Left Atrial Electro-Structural Remodeling Heterogeneity in Persistent Atrial Fibrillation in a Large Mammal Model
  • Thibaut Duparc : In vivo deletion of the IF1 protein: its involvement in lipoprotein metabolism and the development of atherosclerosis
  • Grégory Franck : The mechanisms involved in atherosclerotic plaque erosion processes. The role of NETosis and the MRP8/14 complex in a new model of erosion in mice
  • Laurent Gamba : The role played by the JNK pathway in zebrafish (Danio rerio) heart regeneration
  • Koïchi Kato : Study of SAP97 protein variants in Brugada syndrome
  • Lisa Kitasato : The mechanism of action of Angiomotin-like1 (Amot11) in the regulation of cardiomyocyte proliferation
  • Soazig Le Guyon : The use of a murine model of endovascular prosthesis infection to test new antibiofilm molecules
  • Delphine Mika : Regulation of cardiac pacemaker function by PDE4-encoded isoforms
  • Mélanie Paillard : The structural and functional role of mitochondria-reticulum interactions during ischemia-reperfusion and cardioprotection
  • Thibaut Quillard : The molecular and epigenetic mechanisms of arterial heterogeneity and vascular calcifications
  • Caroline Roney : The Effects of Variability in Pulmonary Vein Electrophysiology and Fibrosis on Arrhythmia Sensitivity and Dynamics
  • Angelo Torrente : The importance of Ca2+ dynamics in the pacemaker mechanism of the sinus node; the role of L-type calcium channels in cyclic AMP synthesis and conduction through the sinus node

Renouvellements de bourse :

  • Brahim Belbellaa : Preclinical development of an innovative in vivo gene therapy protocol for the treatment of cardiomyopathy associated with Friedreich’s ataxia, and studies of pathophysiological mechanisms and biomarkers associated with a cellular deficit or excess of the protein Frataxin
  • Loubina Fazal : Inhibition of Epac1 and its cardioprotective effect in ischemia/reperfusion in mice

2015

  • Alban BaruteauThe characteristics of Rhythm and Conduction Disorders Associated with Congenital Heart Disease involving Atrioventricular DISCOrdance
  • Jason BayerLow-intensity extended surface stimulation (WAYLESS): a new therapy to end lethal cardiac arrhythmias
  • Amandine Cartier-Michaud : Modulation of vascular functions by inhibiting intracellular CD146 interactions
  • Charlotte ErpicumThe role played by the lymphatic system in cardiovascular pathologies
  • Loubina Fazal : The effects of Epac1 inhibition in a murine ischemia/reperfusion model
  • Rebecca GentekSelf-renewal of resident macrophages as a critical factor for cardiac regeneration
  • Kateryna Kyrylkova : Biological role of a stress-response gene Pw1/Peg3 in cardiac physiology
  • Emelyne LecuyerStudy of the cholesterol-lowering function of human gut microbiota in a murine model of atherosclerosis
  • Daniel Romero : Optimization of risk stratification and new therapeutics for subjects with from Brugada syndrome: the development and validation of new tools based on signal processing techniques, mathematical modeling and simulation
  • Pierre Sicard : The roles played by of Gadd45 y in heart failure
  • Grace Thomas-Noguera : Functional characterization of SLC44A2, a new gene associated with Venous Thrombosis

Renouvellement de bourse 

  • Nicolas Diguet : The role of Angiomotin-like1 (Amotl1) in the regulation of cardiomyocyte proliferation
  • Adèle FaucherreStudy of the role of the Piezo1b mechanosensitive ion channel during cardiogenesis in zebrafish
  • Julie Favre : Novel role of the estrogen receptor Erα in flow-dependent dilation of resistance arteries: the importance of membrane signaling
  • Sarah Karam : Overexpression of a phosphodiesterase-4 to prevent heart failure and arrhythmias

2014

  • Julien BarcThe genetics and pathophysiology of sudden cardiac death: new approaches
  • Richard BaylesErythrophagocytosis and Atherosclerosis
  • Frédéric BoalThe role played by phosphatidylinositol 5-phosphate (PtdIns5P) in cardiac remodeling: therapeutic perspectives
  • Aline Chevallier : The roles played by sphingosine-1-phosphate in retinal angiogenesis
  • Adèle Faucherre : Study of the role played by the mechanically activated Piezo2a ion channel during cardiogenesis in zebrafish
  • Julie FavreNovel role of the estrogen receptor Erα in flow-dependent dilation of resistance arteries: the impact in aging
  • Kiave Yune Ho Wang Yin : Inflammatory factors and post-ischemic cardiac remodeling
  • Sarah Karam : Overexpression of a phosphodiesterase-4 to prevent heart failure and arrhythmias
  • Olivia LenoirAn exploration of the determinants and role played by endothelial autophagy in hypertensive heart disease and nephropathy
  • Mariana Mirabel : Myocardial involvement in acute rheumatic fever: an assessment using modern imaging and immunology techniques
  • Emanuela Repetto : An exploration of the emerging world of non-coding RNAs as novel functional mediators and biomarkers for atherosclerosis
  • Sonia Stefanovic : Unraveling the genetic and epigenetic signature of myocardial lineages in the venous pole region
  • Florence Tatin : Molecular mechanisms regulating valve formation in the vascular system and their dysfunction in association with obesity
  • Elsa Vanhecke : GLP-1 and angiogenesis: diabetic retinopathy and safety of diabetes treatment
  • Mariana Varna : Nanosystems for thrombolytic therapy

Renouvellement de bourse 

  • Pierre JoanneDevelopment of a cellularized biomaterial consisting of collagen nanofibers and cardiac progenitors for the treatment of heart failure

2013

  • Brahim Belbellaa : Développement d’une stratégie innovante pour le traitement de l’ataxie de Friedreich par thérapie génique in vivo à l’aide de vecteur viraux recombinant AAV 
  • Karim Belmokhtar : Rôle du Récepteur aux AGEs (RAGE) dans l’apparition des calcifications vasculaires Urémiques 
  • David Benoist : Origines anatomiques et mécanismes responsables d’arythmies ventriculaires dans l’insuffisance cardiaque droite 
  • Brunella Cristofaro : Molecular specification of collateral arteries formation 
  • Joana Raquel Delgado Martins : Sensing pressure with ion channels: role of piezo 1 in arterial mechanotransduction 
  • Ji Gao-Desliens : Développement du premier inhibiteur de l’aminopeptidase A actif par voie orale, comme agent antihypertenseur à action centrale 
  • Simon Guiraud : Pathophysiologie de l’atteinte cardiaque et vasculaire chez des souris HANAC Col4a1 
  • Pierre Joanne : Mise au point d’un biomatériau cellularisé constitué de nanofibres de collagène et de progéniteurs cardiaques pour le traitement de l’insuffisance cardiaque 
  • Mathilde Keck : Canal calcique ORAI3 dans le cardiomyocite normal et hypertrophié 
  • Julie Lafaurie-Janvore : Rôle du Complexe LINC dans la Mécanotransduction des Cellules Endothéliales 
  • Laeticia Lichtenstein : Caractérisation du récepteur P2Y13 dans le développement de l’athérosclérose 
  • Thomas Joseph Moore-Morris : Endocardial cell fate decisions underlying congenital valve defects 
  • Gaëlle Odelin : Modèle murin de valvulopathie : étude du rôle du gène Krox20 dans le développement des valves cardiaques 
  • Julien Viaud : Rôle des GTPases de la famille Rho et des phosphoinositides dans la genèse des plaquettes sanguines 

Renouvellements de bourse : 

  • Ana Llach Martinez : Implication de la protéine Epac dans les altérations du calcium intracellulaire et arythmies 
  • Eloi Marijon : Dépistage Familial systématique en cas de Mort Subite : Application en population 

2012

  • Dong Broqueres-You : Post-ischemic neovascularization and guidance molecules: the role of nervous system restoration in the presence of diabetes
  • Caroline DesmetzInflammation and atherosclerosis: the repertoire and functions of arterial wall resident B cells during human atheromatous disease
  • Virginie DeswaerteImmunomodulation of cholesterol metabolism and the impact on atherosclerosis
  • Fabio Fernandes RosaThe genetics of primary hyperaldosteronism
  • Nathalie Gaborit : Age-related cardiac conduction abnormalities: roles of Iroquois transcription factors in congenital heart diseases-associated arrhythmias
  • Stéphanie Gayral : The role played by phosphoinositide 3-Kinase Cllα in smooth muscle cells: is there involvement in arterial wall pathologies?
  • Anne Leclercq : Study of the role played by endothelial cells in thoracic aortic aneurysmal lesions
  • Ana Llach Martinez : The involvement of Epac in intracellular calcium alterations and arrhythmias during heart failure
  • Laurine Marger-Marienne : Study of the differentiation of adult muscle stem cells into pacemaker myocytes: towards a cell therapy for cardiac automatism disorders
  • Eloi MarijonRoutine Family Screening for Sudden Cardiac Death: Application in the population
  • Ludovic Martin : Identification of the Nav1.5 sodium channel intracellular regulatory pathways: the therapeutic impact for cardiac arrhythmias 
  • Antoine Muchir
    • *Study the integrity of the nuclear envelope as a key mediator of MAP kinases activation 
    • *Identify and evaluate molecular determinants of cardiac dysfunction in pathologies of the nuclear envelope 
    • *Identify novel therapies for the cardiac pathologies of nuclear envelope 
  • Catherine YzydorczykThe involvement of hemodynamics and arterial oxygen pressure in the induction of ectopic mineralization

Research grant renewals : 

  • Delphine Ciais : Identification of those BMP9/BMPR2 targets involved in the pathophysiology of pulmonary hypertension
  • Céline MiasThe role played by the ephrin-B1 protein in cardiac tissue aging

2011

  • Chiara Alfarano : The role played by apelin in myocardial energy remodeling: pathophysiological aspects and therapeutic perspectives
  • Delphine Ciais : Identification of those BMP9/BMPR2 targets involved in the pathophysiology of pulmonary hypertension
  • Nathalie ClémentDefining those signaling pathways downstream of AC8 that lead to the migration of VSMCs in an inflammatory context
  • Zeineb Es-Salah-Lamoureux : The hERG cardiac potassium channel: from biophysics to therapeutics
  • Sophie Gilibert : The role played by the SR-BI receptor in the endothelial cell: involvement in the development and regression of aherosclerotic plaque
  • Jean-François Le Garrec Quantitative analysis of cardiomyocyte polarity and modeling of cardiac chamber formation
  • Xavier Loyer : Endothelial regulation of microRNAs in vitro and in vivo by trimming and oxidized LDLs: a potential role in atherosclerosis
  • Maria Machado : Endothelial regulation of microRNAs in vitro and in vivo by trimming and oxidized LDLs: a potential role in atherosclerosis
  • Céline Mias : The role played by the ephrin B1 protein in cardiac tissue aging
  • Maryline Moulin : The involvement of the mitochondrial permeability transition pore in early pathophysiological mechanisms of cardiovascular pathologies
  • Marie Rouanet-Gueguen : N
    • New roles of PARs (Proteinases-Activated Receptors) in vascular biology
  • Sonia Séverin : Mechanisms controlling platelet formation and activation: the role of class III Pl3K, Vps34 and its product Ptdlns3P
  • Richard Walton : Purkinje fibers as a radiofrequency ablation target for sudden cardiac death prevention

Research grant renewals:

  • Stéphane Doly : Serotonin 5-HT2B receptors and valvulopathy thrombose: application to cardiovascular pathology 
  • Cristina Espinosa Molina : The role played by phosphodiesterases (PDEs) in the vulnerability of human atria to the development of atrial fibrillation

2010

  • Elise Belaidi : The role played by cyclophilin D in protecting against myocardial ischemia-reperfusion: between mitochondrial permeability transition and reticulum stress
  • Stéphane Doly : Serotonin 5-HT2 receptors and valvulopathy
  • Cristina Espinosa Molina : The role played by phosphodiesterases type 4 (PDE4) in cAMP, and by calcium dynamics in atrial fibrillation
  • Gilles Kauffenstein : The role played by extracellular nucleotides in the local regulation of vascular tone and remodeling
  • Claire Crola-Da Silva : The little-known role of cardiac fibroblasts in protecting the heart during infarction. Study using a cardiomyocyte model in co-culture
  • Pauline Parisot : The genetic and cellular basis of coronary artery development: involvement of the second heart field
  • Cathy Quemener : Study of the roles and mechanisms of action of CXCL4, CXCL4L1 and CXCL4 mutants in vascular development
  • Kevin Retailleau : Filamin A and arterial mechanotransduction

Research grant renewal :

  • Cara Büsst : The role played by L-WNK1 in regulating ion transport in the distal nephron

2009

  • Magali Berthouze : Β-adrenergic receptors and the cardiac pathophysiology of Epac
  • Isabelle Brunet : Dynamic study of neurovascular interactions during murine development 
  • Cara Büsst : The role played by L-WNK1 in regulating ion transport in the distal nephron
  • Matthias Canault : Identification of a process to improve the preservation of platelets for transfusion at 4°C. An assessment of the role played by CD40 ligand (CD40L) in the propagation and amplification of the prothrombotic inflammatory state in coronary artery disease. 
  • Claire Crola-Da SilvaThe little-known role of cardiac fibroblasts in protecting the heart during infarction. Study using a cardiomyocyte model in co-culture
  • Nadjia Kachenoura : A comparative study of cardiac CT and stress ultrasound in patients with suspected acute coronary syndrome: developments, contributions and validations of new quantitative image processing analysis methods
  • Alexandre Marchand : The role played by calcium in cardiovascular remodeling: the involvement of microRNAs in cardiovascular pathologies and a study of new therapeutic targets
  • Benjamin Richard : Nexin-1 protease and heart failure
  • Soraya Taleb : The role played by SOCS3 in immune response modulation and the development of atherosclerosis
  • Florence Teillet : Structural studies of Soluble Guanylate Cyclase, a key cardiovascular system enzyme

Research grant renewals:

  • Frédéric Adam : The molecular and cellular mechanisms of JNK1 and JNK2 mitogen-activated protein kinases in thrombosis: application to cardiovascular pathology
  • Cécile Fligny : The role played by tissue transglutaminase in the progression and regression of renal and myocardial collagenous fibrosis in response to hypertensive stress

2008

  • Frédéric Adam : The involvement of Mitogen-Activated Protein Kinase JNK1 in the pathophysiology of hemostasis and thrombosis
  • Abeer El Wakil : The impact of mechanisms controlling functional zonation of the adrenal cortex on the pathophysiology of hypertension
  • Cécile Fligny : The role played by tissue transglutaminase in the progression and regression of renal and myocardial collagenous fibrosis in response to hypertensive stress
  • Jean-Marc Hyvelin : Intrastent myointimal hyperplasia: the effect of heme oxygenase-1 induction
  • Ana Pena Ruiz : An exploration of the influence of polymorphism *2 of the gene encoding cytochrome 2C19 on the response to clopidogrel in young coronary patients (AFIJI Cohort): the CLOVIS 2 study
  • Nathalie Sabaa-Mettoudi : RNA interference control of embryonic and pathological angiogenesis
  • Yannis Sainte Marie : Study of the role played by NOS1 in cardiac contractile function and arrhythmia occurrence in a model of myocardial infarction v
  • Kyoji Urayama : Does PKR1 invalidation in the epicardium have adverse cardiovascular consequences ?

Research grant renewal:

  • Nathalie Beaufort : The role played by endogenous and microbial proteolytic activities as determinants of fibrinoid vegetation fragmentation and tissue destruction in infective endocarditis
  • Violaine Griol-CharhbiliThe role played by aldosterone in cardiovascular function: the effect of endothelial mineralocorticoid receptor overexpression

2007

  • Constandina Arvanitis : Characterization of the molecular mechanisms involved in regulating catecholanin release at the neurocardiac synapse: defining the inhibitory role of the a2-adrenergic system
  • Nathalie Beaufort : The role played by endogenous and bacterial proteolytic activities as determinants of fibrinoid vegetation frangmentation and tissue destruction in infective endocarditis
  • Caroline Cieniewski-Bernard : Towards the characterization of new markers for post-infarction left ventricular remodeling 
  • Violaine Griol-Charhbili : The role played by aldosterone in cardiovascular function: the effect of endothelial mineralocorticoid receptor overexpression
  • Valérie Perrot : Rho protein exchange factors as novel targets of therapeutic interest in arterial hypertension
  • Francesca Rochais : Characterization of factors involved in the regulation of cardiac progenitor cell fate during development
  • Marcela SzoposMathematical modeling of the influence of aortic arch geometry on blood pressure.

Research grant renewal : 

  • Mélanie Eyries : Quantification of angiogenesis using automatic image analysis.
  • Stéphanie Michineau : The involvement of the P13-kinase/Akt pathway in aneurysmal stabilization

2006

  • Nicolas Elie : Quantification de l’angiogenèse par analyse automatique d’images. 

  • Mélanie Eyries : Implication de la voie de signalisation des Bone Morphogenetic Proteins dans la physiopathologie de l’hypertension artérielle pulmonaire. 

  • Caroline Fribourg : Study of VWF binding to OPG and identification of the VWF domain responsible for this binding; the role played by VWF in regulating OPG levels, and the consequences of decreased OPG levels in VWF-deficient mice.

  • Socorro Vanesca Frota Madeira : Are PPARs essential mediators in activatiing endothelial NO synthase in response to physiological agonists and plant polyphenols ?

  • Witold Kilarski : Comparative profiling of endothelium proteome in normal and granulation tissue vasculature. 

  • Stéphanie Michineau : The involvement of the P13-kinase/Akt pathway in aneurysmal stabilization. 

  • Catherine Plin : The effect of GSK-3ß protein on myocardial ischemia-reperfusion-induced mitochondrial permeability transition pore opening

  • Marcela Szopos : Mathematical modeling of the influence of aortic arch geometry on blood pressure. 

Research grant renewal : 

  • Xavier Houard : The role played by proteolysis in the progression of degenerative vascular pathologies

2005

  • Carole Devaux : Characterization of the CRP-LXR pathway in human vascular smooth muscle cells: involvement in arterial remodeling processes. 

  • Meyer Elbaz : Evolution of the Non-Stenotic Lesions Responsible for Acute Coronary Syndrome: study conducted using Endocoronary ultrasound

  • Lars Erdtmann : Hepatitis C virus NS2 protein induces myocarditis in a transgenic mouse model.

  • Xavier Houard : The role played by proteolysis in the progression of vascular pathologies.
  • Elizabeth A.V. Jones
    -The creation of blood vessels using microfluidic pumps
    -Direct observation of arteriovenous malformations by videomicroscopy in genetically modified murine embryos.
  • Jérôme Leroy : The role of type 4 phosphodiesterases in heart failure. 
  • Caroline Pinet : The mechanism of action of thrombin on cardiac sodium channels.
  • Anne Pizard : The kallikrein-kinin system, peptidergic vasodilatation and vascular diseases.

Research grant renewal : 

  • Marianne Abi Fadel : Characterization of the role of the PCSK9 gene in the pathophysiology of familial hypercholesterolemia and its cardiovascular complications

2004

  • Marianne Abi Fadel : Characterization of the role of the PCSK9 gene in the pathophysiology of familial hypercholesterolemia and its cardiovascular complications.
  • Céline Fassot-Lucht : Study of the aortic transcriptome. Research into the determinants of arterial stiffness. tude du transcriptome aortique. Recherche des déterminants de la rigidité artérielle. 
  • Jeanne Flavigny : Overexpression of human NOS1 in mice: the impact o contractility and calcium movement.
  • Claudine Menard : Preclinical study of heart failure using cell therapy.
  • Eric Morel : The role played by the (cAMP-activated) Epac exchange factor in cardiac hypertrophy and heart failure.
  • Mylène Potier : Reendothelialization mechanisms: the role of osteopontin in estrogen action.
  • Radia Tamarat : Analysis of the effects on renal tissue of targeted MR overexpression, specifically in vascular cells.

Renouvellements de bourses : 

  • Fanny Bajolle : The involvement of the anterior heart field in the morphogenesis of the murine heart efferent pathway.
  • Nathalie Lalevee-Girard : Electrophysiological study of cardiac activity in Drosophila during development. 

2003

  • Carole Amant : Study of Hypoxia-Induced Factor-1 stabilization and activation by phosphorylation: clinical applications and gene therapy of angiogenesis and cardiac and peripheral ischemia.
  • Fanny BajolleMorphogenesis of the efferent pathway (aorta and pulmonary trunk) in the murine heart.
  • Olivier Blanc-BrudeSurvivin in atherosclerosis.
  • Angelika de Bree : Folate, choline and betaine intakes and cardiovascular diseases.
  • Ariane Galaup : Molecular mechanisms of angiogenesis: the role played by ANGPTL-4 in physiological and pathological angiogenesis.
  • Nathalie Lalevée-GirardFunctional cardiogenesis in Drosophila: an electrophysiological study.
  • Nathalie Petit : Pathophysiological mechanisms of cavernous angiomas
  • Béatrice Thomas : Study of the molecular phenotype of the pathological endothelial cell: application to inherited vascular diseases

Research grant renewals : 

  • Sophie Creuzet : The neural crest and the cardiovascular system.
  • Nermine Lila : HLA-G expression and heart transplantation in humans.

2002

  • Onnik Agbulut : Adult stem cell transplantation in the treatment of heart failure
  • Sébastien Alcolea : The distribution and addressing mechanisms of KvLQT1 potassium channels in the human heart.
  • Olivier Barbier, Ph. D : PPARa activators induce the expression of UDP-glucuronosyltransferases metabolizing liquid mediators of inflammation – the anti-inflammatory role played by lipid-lowering fibrates. 
  • Giuseppina Caligiuri : The role played by immunity in arterial remodeling.
  • Sophie Creuzet : The neural crest and cardiovascular system.
  • Pascal DraneDysfunction of nuclear receptor transactivation mechanisms causing neurological and cardiac deficiencies: the SP/CS model.
  • Barbabas Gellen : Role of serca over expression in the time course of left ventricular remodelling following myocardial infarction in rats.
  • Nermine Lila : HLA-G expression and heart transplantation in humans.
  • Laurence Mabile : Hormonal and nutritional mechanisms regulating hepatic lipase expression in humans.
  • Gunsel Canan Nebigil-Desaubry : Involvement of the serotonin 5-HT2B receptor in cardiomyopathy.

2001

  • Salia Cherifi : Study of the physicochemical and magnetic properties of small systems using an innovative microscopy technique: photoelectric effect microscopy (PEEM), and the development of instrumentation to improve its spatial resolution.

  • Marie-Claude Clochard : Study of the beneficial effects in medicine of the radiochemical grafting of peptides onto a biodegradable polymer substrate. 

  • Bruno Delorme : Muscle stem cells for cardiac cell therapy.
  • Julien Ghislain : Identification of those elements controlling the expression of the Krox20/Egr2 transcription factor that plays an essential role in the development of vertebrate central and peripheral nervous systems.
  • Abdeslem Hallou : Control of primary bioradical mechanisms: new contributions to pathophysiology and therapeutics.
  • Matteo Elia Mangoni : Physiopathology of the cardiac rhythm.
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Foundations and awards

Exposants / Botiaux-Dulac

Action contre la faim

    Foundations and awards

    Exposants / Écologie / Environnement

    Allianz

      Foundations and awards

      Exposants / Écologie / Environnement

      Champagne Deutz

        Foundations and awards

        Prix / Écologie / Environnement

        Daniel Jouvance

          Foundations and awards

          Prix / Écologie / Environnement

          Écologie d’avenir

            Foundations and awards

            Prix / Écologie / Environnement

            Édouard Bonnefous

              Foundations and awards

              Prix / Botiaux-Dulac

              Fondation Feuilhade

                Foundations and awards

                Prix / Botiaux-Dulac

                Fondation Luciole

                  Foundations and awards

                  Exposants / Botiaux-Dulac

                  France Bleu

                    Foundations and awards

                    Exposants / Botiaux-Dulac

                    Yves Rocher